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Research Scientist-50% onsite

  • Location: Lawrenceville
  • Job Type:Contract

Posted about 1 month ago

  • Expiry Date: 28 January 2023
  • Referral: 221330@accuick.com

Job Description:

  • We are seeking an innovative scientist to join our Informatics Predictive Sciences team.

  • This group of computational biologists is responsible for advancing company’s industry-leading Early Clinical Development pipeline through the strategic application of cutting-edge bioinformatics approaches.

  • This individual will work closely with other groups in R&D to analyze pre-clinical and clinical molecular datasets, data to develop patient enrichment strategies, novel biomarkers, diagnostics, and guide drug development decisions.

  • Informatics and Predictive Sciences (IPS) has a mission to drive predictive informatics research across company.

  • The role of IPS encompasses a broad range of computational research, from cutting-edge bioinformatics to discover new therapeutic targets, to applied machine learning to optimize clinical trials and predict patient outcomes.

  • Our team focuses on cutting edge informatics research to progress company' Early Development clinical pipeline.

Roles and responsibilities:

  • Performing computational biology analysis for exploration and interpretation of omic datasets, including bulk and single-cell RNASeq, DNA methylation, Exome/Genome sequencing, cytokine, and proteomic data.

  • Integrative analysis across different molecular, clinical and demographic parameters to identify relevant biomarkers (e.g., response, toxicity and pharmacodynamic markers) in clinical studies.

  • Development and application of classification methods to select clinically relevant patient segments via application of machine learning methods to molecular profiling data.

  • Leveraging internal and external datasets to augment data analysis and findings derived from clinical studies.

  • Presentation and reporting of methods, results, and conclusions to a publishable standard.

  • Participating in wider group endeavors concerning the elucidation of disease biology, compound mechanisms of action, drug resistance and prediction of target indications.

Qualifications:

  • PhD (preferable 2+ years post-doctoral experience) in computational biology / bioinformatics, statistics, computer science or related fields, from a recognized higher-education establishment

  • Prior experience (4+ years) of analysis, integration and interpretation of high-throughput data supported by high-quality publications.

  • Expertise in statistical programming and data manipulation, using e.g., R/Bioconductor, Matlab, Python, plus good knowledge of contemporary database structures.

  • Expertise in statistical analysis, analysis of longitudinal data, data deconvolution and machine learning techniques (semi-supervised approaches is a plus).

  • Experience with version control and high-performance computing, including cloud computing and/or big data analytics platforms would be advantageous.

  • Scientific curiosity, collaborative spirit and proven ability to contribute beyond personal projects.

  • Ability to understand and communicate the output of computational research to multi-disciplinary scientific teams.

  • The position presents a unique opportunity to experience research in an industry setting and to contribute to helping patients with unmet medical need, while maintaining a link to academic research (publication is encouraged).

  • 5 measurable skills or experiences that manager wants to see on every resume.

  • PhD in computational biology, bioinformatics, statistics, computer science or related fields

  • 4+ years of experience in analyzing, integrating and interpreting high-throughput data

  • Expertise in statistical programming and data manipulation, using e.g. R/Bioconductor, Matlab, Python, plus good knowledge of contemporary database structures.

  • Expertise in statistical analysis, analysis of longitudinal data, data deconvolution and machine learning techniques

  • Experience with version control and high-performance computing, including cloud computing and/or big data analytics platforms.

About ASK: ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities

ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.