- Expiry Date: 23 September 2022
- Referral: email@example.com
The Lead Discovery and Optimization Group within Small Molecule Drug Discovery in San Diego focuses on delivering novel therapeutics for disease intervention by engaging E3 ubiquitin ligases for targeted protein degradation.
We are seeking a highly driven Research Associate/Senior Research Associate to assist in the identification and characterization of drug candidates for the treatment of human diseases.
The successful candidate will work collaboratively in a multi-disciplinary environment to carry out cell-based assays in support of small molecule discovery for pre-clinical development.
Responsibilities will include but are not limited to the following:
Conduct routine medium and high-throughput biochemical and cellular assays to characterize compounds
Establish stable cell lines via lentiviral transduction and maintain mammalian cell lines
Conduct routine molecular and cellular experiments including DNA/RNA/protein extraction, qPCR, ELISA, Western blot, and immunoprecipitation
Assist senior researchers in executing, conducting analyses, and reporting results of experiments
Familiarity with literature and internal best practices to identify opportunities to improve productivity and quality of work
Analyze, troubleshoot, and recommend corrective actions for routine problems
Maintain an accurate, comprehensive, and current laboratory notebook
Write protocols, procedures and technical reports
Communicate results via written reports and oral presentations
BS with 2+ years or MS in cell biology or related scientific discipline
Expertise in mammalian cell culture, plate-based cellular assays, immunoblotting, lentiviral infection, cellular transfection, and basic molecular biology techniques
Experience with medium and high throughput screening is highly preferred
Experience with targeted protein degradation assay is a plus
Familiarity with automation instruments and multi-mode plate readers
Outstanding problem-solving and organization skills.
Effective team player and strong individual contributor
Self-driven, flexible, pragmatic and able to handle multiple tasks while delivering high quality data.
About ASK: ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities
ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.
Full Name: Sufiyan Sheth
Email ID: firstname.lastname@example.org