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Associate Research Scientist

  • Location: Redwood City
  • Job Type:Contract

Posted 27 days ago

  • Expiry Date: 30 January 2022

​​​Job Description:

Specific Responsibilities

  • Support bioconjugation activities using various random and site-specific conjugation technologies.

  • Production, purification, and characterization of ADCs on research- and early-development scales.

  • Development and optimization of conjugation protocols utilizing novel chemistries and technologies.

  • Protein expression of various antibodies and antigens in multiple expression systems.

  • Protein purification utilizing variety of methods including affinity, ion-exchange, hydrophobic interaction, size-exclusion chromatography, and tangential flow filtration.

  • Record and communicate findings in a timely manner.

Requirements

  • BS degree with 5+ years of industry experience or MS degree with 2+ years of industry experience. The degree should be in Biochemistry, Chemistry, or related disciplines.

  • Experience in bioconjugation methods (lysine, inter-chain cysteine and/or site-specific cysteine and other).

  • Experience in production, purification and characterization of ADCs on research scale (0.5-15 mg) and medium scales (100-500 mg).

  • Experience in protein expression and purification on AKTA platforms.

  • Experience in development of purification strategies using various chromatographic techniques such as affinity, size exclusion, ion-exchange, hydrophobic interaction, and tangential flow filtration.

  • Develop and implement methods for purification and in-depth biochemical characterization of therapeutic candidates and reagents (RP-HPLC, LC-MS, SDS-PAGE, western analysis, ELISA).

  • Highly organized, motivated, ability to work independently and in collaborative teams.

  • Demonstrated record of scientific accomplishments and publications.

  • Excellent time management and organizational skills.

About ASK:ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities

ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.