- Expiry Date: 30 January 2022
Support bioconjugation activities using various random and site-specific conjugation technologies.
Production, purification, and characterization of ADCs on research- and early-development scales.
Development and optimization of conjugation protocols utilizing novel chemistries and technologies.
Protein expression of various antibodies and antigens in multiple expression systems.
Protein purification utilizing variety of methods including affinity, ion-exchange, hydrophobic interaction, size-exclusion chromatography, and tangential flow filtration.
Record and communicate findings in a timely manner.
BS degree with 5+ years of industry experience or MS degree with 2+ years of industry experience. The degree should be in Biochemistry, Chemistry, or related disciplines.
Experience in bioconjugation methods (lysine, inter-chain cysteine and/or site-specific cysteine and other).
Experience in production, purification and characterization of ADCs on research scale (0.5-15 mg) and medium scales (100-500 mg).
Experience in protein expression and purification on AKTA platforms.
Experience in development of purification strategies using various chromatographic techniques such as affinity, size exclusion, ion-exchange, hydrophobic interaction, and tangential flow filtration.
Develop and implement methods for purification and in-depth biochemical characterization of therapeutic candidates and reagents (RP-HPLC, LC-MS, SDS-PAGE, western analysis, ELISA).
Highly organized, motivated, ability to work independently and in collaborative teams.
Demonstrated record of scientific accomplishments and publications.
Excellent time management and organizational skills.
About ASK:ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities
ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.