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Associate Research Scientist

  • Location: San Diego, San Diego County, California
  • Job Type:Contract

Posted 13 days ago

  • Expiry Date: 16 August 2021

​​Job Description:

  • We are seeking an Associate Research Scientist with a strong interest in protein expression and bioprocess development to join the protein science group in the Discovery Biotherapeutics department at our new state-of-the art facility in San Diego, CA. The qualified candidate will be responsible for mammalian protein expression and bioprocess development in both shake flasks and automated mini-bioreactors, and other lab related activities as assigned.

Responsibilities will include, but are not limited to, the following:

  • Expression of antibodies (bi-/multi-specific antibodies) and other recombinant proteins in transient and stable formats to support biotherapeutic drug discovery projects.

  • Mammalian cell culturing in both shake flasks and automated mini-bioreactors, along with HT automated liquid handling systems.

  • Process development and optimization for batch and fed-batch bioreactor and shake flask expressions.

  • Transient protein expression as well as stable pool and single cell cloning generation.

  • Purification and biophysical characterization of analytical scale expression samples.

  • Ensure accurate registration of protein expression samples and associated data into electronic inventory system and electronic laboratory notebook.

Requirements:

  • Candidate should have a B.S or M.S in Biology, Biochemistry, Bioengineering or a related field with at least 2-4 years of relevant experience in an industry setting.

  • Hands on experience with mammalian cell (CHO, HEK) culture, transient and stable transfection and protein characterization.

  • Experience with operating Ambr mini-bioreactor and bench scale bioreactor, HT automation and analysis, bioprocess development and process optimization is highly desirable.

  • Proficiency with Design of experiment (DOE) and DOE analysis software will be a plus.

  • Working knowledge and familiar with protein and antibody purification and analytical assessment.

  • Excellent data management skills and a demonstrated ability to manage large structure datasets using

  • Excellent written and oral communication skills including ability to present scientific data in group setting.

  • Excellent organization to multi-task and manage multiple projects.

Functional/Scientific/Technical Skills:

  • Implement and validate protocols.

  • Mastery of basic lab skills.

  • Reviewing literature for technical support.

  • Data analysis.

  • Familiarity with data retrieval and input from database.

Tasks and Responsibilities:

  • With assistance, executes experiments, conducts analysis and reports results.

  • Familiarity with work and business practices to be able to identify and troubleshoot routine problems.

Discretion/Latitude:

  • Requires less direction to complete assigned tasks.

  • Consults colleagues for advice on issues.

Creativity and Problem Solving:

  • Recognize unexpected outcome/problems; communicates and works with supervisor to solve.

  • Learn from the past experience to improve the current process.

Teamwork and Influence:

  • Communicates with peers and supervisors.

  • Begin to communicate with departments and customers.

  • Works in context of immediate work group or team.

Organizational Impact:

  • Has a direct impact on workgroup performance.

  • Impact is achieved by contributing to workgroup.

Behavioral Competencies:

  • Commitment to quality Demonstrates adaptability

  • Develops oneself Drive for results

  • Effective speaking Fosters teamwork

  • Listens to others Prepares written communications

  • Shows work commitment Uses functional/technical expertise

  • Works efficiently

About ASK: ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities

ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.